New Method for Spectrophotometric Determination of Lisinopril in Pure Form and in Pharmaceutical Formulations
نویسنده
چکیده
Synthesis new organic azo dye as reagent 3-((4-acetyl-3-hydroxyphenyl) diazenyl)-4-amino-N-(5-methylisoxazol3-yl)benzene sulfonamide (SDA) and Analytical Study of Co(II), Ni(II) and Cu(II), metals complexes. The reagent and its complexes were characterized by elemental analysis, UV-Vis, and molar conductivity measurements. The data show that the complexes have the composition of [MR]X2 type. The conductivity data for all complexes are consistent with those expected for an electrolyte. Octahedral environment is suggested for metal complexes. *Corresponding author: Mohauman Mohammad Al-Rufaie, Department of Chemistry, College of Science, Kufa University, Iraq, Tel: 07809086646; E-mail: [email protected] Received January 23, 2016; Accepted February 12, 2016; Published February 16, 2016 Citation: Al-Rufaie MM (2016) Synthesis and Analytical Studies of 3-(4-Acetyl3-Hydroxyphenyl) Diazenyl)-4-Amino-N-(5-Methylisoxazol-3-Yl)Benzene Sulfonamide with Some Metals. Mod Chem appl 4: 175. doi:10.4172/2329-6798.1000175 Copyright: © 2016 Al-Rufaie MM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
منابع مشابه
Derivative Spectrophotometric Method for Determination of Losartan in Pharmaceutical Formulations
Losartan, a highly effective blood pressure lowering agent, has been widely used for the treatment of hypertension. A fast and reliable method for the determination of losartan was highly desirable to support formulation screening and quality control. A first derivative UV spectroscopic method was developed for determination of losartan in the tablet dosage form. The first derivative spectrum r...
متن کاملApplication of Mixed Micelle-Mediated Extraction for Selective Separation and Spectrophotometric Determination of P-Aminophenol Impurity in Pharmaceutical Formulations
A procedure for separation/preconcentration of para-aminophenol (PAP) in pharmaceutical formulation, based on cloud point extraction (CPE) as a prior step to determination by UV-Vis spectrophotometry has been developed. The analyte reacted with 4-dimethylamino benzaldehyde (DAB) in acidic media to form a shift base, which were separated and preconcentrated in a mixed micelle of the anionic surf...
متن کاملAdaptive neuro-fuzzy inference system (ANFIS) applied for spectrophotometric determination of fluoxetine and sertraline in pharmaceutical formulations and biological fluid
The UV-spectrophotometric method of analysis was proposed for simultaneous determination of fluoxetine (FLX) and sertraline (SRT). Considering the strong spectral overlap between UV-Vis spectra of these compounds, a previous separation should be carried out in order to determine them by conventional spectrophotometric techniques. Here, full-spectrum multivariate calibrations adaptive neuro-fuzz...
متن کاملSpectrophotometric Determination of Corticosteroids and Its Application in Pharmaceutical Formulation
A simple, sensitive and economically viable spectrophotometric method for the determination of corticosteroids (predinsolone {PSL}, dexamethasone {DEX}, prednisone {PS}, betamethasone sodium phosphate {BEP} and hydrocortisone {HYD} has been developed. The method involves the oxidation of corticosteroids by iron (III) and subsequent complexation of iron (II) with potassium hexacynoferrate (III),...
متن کاملKinetic spectrophotometric method for the determination of silymarin in pharmaceutical formulations using potassium permanganate as oxidant.
A new simple and sensitive kinetic spectrophotometric method for the determination of silymarin in pure form and in pharmaceutical formulations is described. The method is based on the oxidation of the drug with potassium permanganate at pH 7.0 +/- 0.2. The reaction is followed spectrophotometrically by measuring the decrease in the absorbance at 530 nm. The calibration graph is linear in the r...
متن کاملSelective Cloud Point Extraction for the Spectrophotometric Determination of Cetylpyridinium Chloride in Pharmaceutical Formulations
In this work, we developed a simple and selective method for separation and spectrophotometric determination of trace amounts of cetylpyridinium chloride (CPC) in pharmaceutical products using cloud point extraction (CPE) technique. The method is based on cloud point extraction of the CPC in alkali conditions using of nonionic surfactant Triton X-114. Under selected conditions, the calibration ...
متن کامل